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Dangerous interactions

Although many drugs are safe on their own, they can become dangerous and even life-threatening when combined with other substances. The list below contains some common potentially dangerous combinations, but may not include all of them. Certain combinations may be safe in low doses of each but still increase the potential risk of death. Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

Pink Cocaine Stimulants – Ethylone can be potentially dangerous in combination with other stimulants as it can increase one’s heart rateand blood pressure to dangerous levels.
25x-NBOMe & 25x-NBOH

ions with Ethylone should be strictly avoided due to the risk of excessive stimulation and heart strain. This can result in increased blood pressure, vasoconstriction, panic attacks, thought loops, seizures, and heart failure in extreme cases.

Alcohol – Combining alcohol with stimulantscan be dangerous due to the risk of accidental over-intoxication. Stimulants mask alcohol’s depressant effects, which is what most people use to assess their degree of intoxication. Once the stimulant wears off, the depressant effects will be left unopposed, which can result in blackouts and severe respiratory depression. If mixing, the user should strictly limit themselves to only drinking a certain amount of alcohol per hour.

DXM – Combinations with DXM should be avoided due to its inhibiting effects on serotonin and norepinephrine reuptake. There is an increased risk of panic attacks and hypertensive crisis, or serotonin syndrome with serotonin releasers (MDMA, methylene, mephedrone, etc.). Monitor blood pressure carefully and avoid strenuous physical activity.
MDMA – Any neurotoxic effects of MDMA are likely to be increased when other stimulants are present.

There is also a risk of excessive blood pressure and heart strain (cardiotoxicity). Pink Cocaine
MXE – Some reports suggest combinations with MXE may dangerously increase blood pressure and increase the risk of mania and psychosis.
Dissociatives – Both classes carry a risk of delusions, mania and psychosis, and these risk may be multiplied when combined.
Stimulants – Ethylone may be dangerous to combine with other stimulants like cocaine as they can increase one’s heart rate and blood pressure to dangerous levels.
Tramadol – Tramadol is known to lower the seizure threshold[8] and combinations with stimulants may further increase this risk.
Pink Cocaine – This combination may increase strain on the heart. Pink Cocaine
Serotonin syndrome risk

Combinations with the following substances can cause dangerously high serotonin levels. Serotonin syndrome requires immediate medical attention and can be fatal if left untreated.

MAOIs – Such as banisteriopsis caapi, syrian rue, phenelzine, selegiline, and moclobemide.[9] Serotonin releasers – Such as MDMA, 4-FA, methamphetamine, methylone and αMT.
SSRIs – Such as citalopram and sertraline
SNRIs – Such as tramadol and venlafaxine
5-HTP

Pink Cocaine

There have been deaths related to the use of ethylone, however none caused directly by the substance*